AlphaMol

Welcome to AlphaMol Science Ltd

We are the Intelligent Molecule Creators. We aim at discovering and developing new drug molecules to treat major human disorders and diseases including those against infections, cancers, Alzheimer's disease, diabetes, aging and others. We primarily focus on G protein-coupled receptors (GPCRs) related signalling pathway.

GPCR GPCRs mediate central cellular signalling processes. They are important targets for drug discovery.
Computational drug discovery Computational biology play an essential role in drug discovery.
Innovative biotechnology Innovative Biotechnology for membrane protein are essential for new drug discovery.

FEATURES

AlphaMol combines computational biology, biochemistry, medicinal chemistry, pharmacology, biotechnology and others subjects together, aiming at building up a complete pipeline to advance modern new drug discovery and drug design in an ultimately efficient way. The members of AlphaMol advanced two "first-in-class" drug molecules into clinical trial via computational methods within three years, of which the world-wide patents were granted. Moreover, the members of AlphaMol also invented a series of important biotechnology in the past 20 years. AlphaMol establishes an international outstanding team to make milestones in the areas of both drug discovery and biotechnology.

Innovative biocomputing

The AlphaMol team has long-term successful experience in biocomputing for modern drug discovery. AlphaMol combines different computational methods including system biology, molecular modelling and molecular dynamics to advance new drug discovery in an ultimately efficient way.

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Novel Biotechnology

Our novel technologies include the first optical sensor chip for probing the activation of G protein-coupled receptors, the first silicon chip for automated planar patch clamp measurements, post-translational labelling of cellular proteins, to name a few. More recently, we made another breakthrough in cyroEM.

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Extensive Collaborations

Based on the experience of our team members, AlphaMol have established extensive collaborations with leading pharmaceutical and food companies. In the future, we would like to advance modern drug discovery pipelines with different potential collaborators world wide as well.

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CADD scientists at different levels

A position for computer-aided drug discovery is offered in AlphaMol. A PhD or a MS after 5 years of graduation in Computational Chemistry or related field is required... Reed More

Senior medicinal chemist

The position for senior medicinal chemist requests a M.S. (10-15 years) or PhD (8-10 years) in medicinal chemistry, with extensive drug discovery experience in industry. The successful... Reed More

Pharmacologist

Ph.D. or MS after 5 years of graduation in pharmacology, Immunology, Cell Biology, Molecular Biology or related field with 5+ years or M.S. with 10+ years of relevant experience... Reed More